Endocrine Abstracts

Two patients presented to us with polyuria and polydipsia.Case 1– A 34 year old gentleman was referred with polyuria, polydipsia, diffuse headaches and poor sleep. Initial plasma and urine osmolality were 306 and 272 milliosmol/kg respectively. Water deprivation test demonstrated normal concentrating ability. Starting urinary osmolality was 788 milliosmol/kg, rising to 877 milliosmol/kg. MRI pituitary was normal. Hypertonic saline infusion test prod...

Background: Magnesium, the second most abundant intracellular cation, plays a key role in cellular and metabolic reactions including protein synthesis, neurotransmission and electrolyte balance. There are no specific signs or symptoms of hypomagnesaemia and it can coexist with other electrolyte abnormalities. According to various surveys the prevalence of low Magnesium varies between 2–10% in hospitalized patients. However, there are no clear guidelines about when to scre...